Well, different organisms require different things. A single celled bacteria does not need a lot at all compared to a plant or animal. One cell can support a bacrerium. An animal needs many cells to carry out the functions necessary for it to live.
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All single-celled organisms contain everything they need to survive within their one cell. These cells are able to get energy from complex molecules, to move, and to sense their environment. The ability to perform these and other functions is part of their organization.